"Prajisan": reviews, instructions, application
Why does humanity need hormonal drugs? Hormones (from the Greek "induce", "drive, excite") are the product of the functioning of the endocrine glands. The influence of these substances manifests itself distally, at different distances from the gland in which they are formed. Effects from the effects of hormones are diverse and unique.
In the human body, manya variety of hormones. Sometimes, against the backdrop of various diseases, the activity of the endocrine system may decrease and, as a consequence, their production (hormones) decreases. To bring the situation to normal, hormonal preparations are needed. One of them is Prajisan. Reviews of patients and specialists characterize this substance as an excellent tool for treating diseases of the female sexual sphere.
The drug is a hormone of yellowbody. With his direct involvement there is a change in the phase of the mucous membrane of the uterus: from the state of proliferation it passes into the secretory phase. Thus, "Prajisan" (doctors' reviews and information on instructions for use confirm this) creates optimal conditions for implantation into the mucosa of a fertilized egg.
In addition, under the influence of this hormonedecreases the sensitivity of the uterus to a substance such as oxytocin, relaxes its musculature. Prajisan contributes to the increase of fat stores, increase of the level of insulin (induced and basal), affects the effective utilization of glucose, stimulates the process of accumulation of glycogen in the liver.
Also "Prajdisan" reviews have both goodThe agent, suppressing synthesis of hypothalamic factors of FSH release, LH. In the tissues of the breast, the hormone helps to reduce the permeability of the capillaries, reduces edema of the connective tissue stroma.
In what cases is it appointed?
All the most important and complete information containsabout a hormonal preparation "Prajisan" (capsules) the instruction on application. The reviews, the description of the drug characterize it as very effective in such problems as secondary amenorrhea, infertility caused by a deficiency of lutein, dysfunctional uterine bleeding, a consequence of a lack of progesterone.
Pragisan is widely useda component of hormone replacement therapy in tandem with estrogenic medicines in the post-menopausal period. Also, this hormone is used to support the luteal phase in those cases where additional reproductive techniques are used.
Methods of medicament use
If the level of progesterone is insufficient, capsules"Prajisana" is taken in a daily volume equal to 200-300 mg. Frequency of admission - twice during the day. Determining the duration of the course of therapy is the prerogative of the doctor, everything is very individual and depends on the severity of the state of health.
The daily dose of the drug with a luteal phase deficiency can range from 200 to 400 mg. The duration of therapy is 10 days (strictly 17-26 days of the menstrual cycle).
During the peri-and postmenopause "Prajisan" (reviews of patients claiming high efficacy of the drug) is taken at 200 mg per day in parallel with estrogens. The duration of the course is 10-12 days.
It is possible to use this hormone in the preparation for IVF in the form of capsules for vaginal administration. Duration of admission - until the onset of pregnancy.
In the treatment of infertility, which is caused by luteal insufficiency, the "Prajisan" gel is used. Duration of the course is 10 days.
When and who should refrain from using Prajisan?
Like any hormone, there arecontraindications and the medication "Prajisan". Reviews, instructions the use of this tool is prohibited in those cases when the patient has such pathological problems as porphyria, vaginal bleeding of unknown origin, malignant neoplasms of genital organs or mammary glands.
Contraindicated this medicine and those whosuffers from thrombophlebitis, thrombosis and any other thromboembolic diseases. Do not prescribe "Prajisan" for acute disorders of cerebral circulation and with severe liver disease.
Increased individual sensitivity to the main and auxiliary components of the medication is also a contraindication for taking the drug.
Pregnancy and Prajisan
A separate topic for the conversation is "Prajisan" withpregnancy. Feedback from specialists does not speak of persistent contraindications or evidence. The fact is that the lack of the level of progesterone in the body of a pregnant woman carries the threat of abortion. In such cases, the attending physician will usually prescribe a course of appropriate therapy to enable the woman to safely endure the child. Prajisan is one of the possible options.
If the level of progesterone in a future mother is normal, then the woman will certainly put herself and the child at risk by taking the medication in the first half of pregnancy (16-18 weeks).
Also, one should not overlook the fact that,that taking Prajisan during pregnancy (expert reviews confirm this fact) in the period from 12 to 40 weeks of bearing a baby, the patient risks acquiring serious enough liver diseases.
Patients who took Prajisan talk aboutpresence of some side effects from different organs and systems. The cardiovascular system can respond by increasing blood pressure. From the side of metabolism, pronounced reaction to "Prajisan" (reviews of specialists testify to this) are considered edemas. The digestive system is capable of declaring itself a violation in the functioning of the liver, the development of jaundice. With prolonged use, nausea and vomiting may occur.
Also, when applying Prajisana overlong time may decrease libido, weight gain, pain and feeling of tension in the mammary glands, uterine bleeding (irregularly). Possible reaction of the central nervous system with prolonged admission is depression, skin rash, itching, headaches. Quite often, patients talk about the appearance of a feeling of fatigue after taking the medication.