"PC-Mertz": instructions for use, composition, analogs, reviews

"PK-Mertz" instructions for use is positioned as a drug, the pharmacological properties of which are aimed at the treatment of pronounced nervous disorders (including such chronic forms as Parkinson's disease). As a member of the glutamate NMDA receptor blocker group, the drug also has antiviral effects.

It is noted that when amantadine sulfate, the main active ingredient, is introduced into the body, there is a significant slowdown in the process of dopamine reuptake. Namely: this hormone is able to influence the speed of the natural synthesis of acetylcholyl and, under certain conditions, cause malfunctions in mental algorithms and pinpoint gaps in memory.

PC Mertz: composition and release form

In the pharmacy network the drug comes in the form of:

  • soluble tablets;
  • standard analogs with a film cover;
  • fluids for infusion.

pc merz instructions for use

Each pill, in addition to 100 mg of the basic reagent (amantadine sulfate), contains:

  • microcrystalline cellulose;
  • titanium dioxide;
  • gelatin;
  • magnesium stearate;
  • butyl methacrylate copolymer;
  • starch.

At a slight concentration are also present: lactose monohydrate, derivatives of silicon and sodium, talc and povidone.

As for the solution for intravenous injections, the instructions for use of this pharmacological form of the PK-Mertz drug inform the following:

The tablets are packaged in blisters - 10 pcs. Each, and they, in turn, are placed in cardboard packs (10, 20, 30, 90 and 100 pills each). The solution is sold in polymer bottles, of which in the package can be from one to ten.

How does the drug on the human body?

The structured formula of tricyclic symmetric adamantamine is responsible for providing anti-parkinsonian and antiviral effects. Absorbed, the active ingredient enters into a biochemical relationship with the glutamate NMDA receptors and completely blocks their work. As a result, the stimulation of the non-striatum from the side of the cortical neurons occurs.At the same time, dopamine synthesis is accelerating against the background of an increase in its extracellular concentration.

pc merz description

The natural result of the described reactions becomes a partial “embargo” on the supply of ionized calcium to neurons, and, as a result, the natural destruction of pulsed conductors is prevented.

The drug modulates to a greater extent the state of stiffness, building the “barrier” to the influenza A-class virus is its secondary function (for other pathogens, the components are unstable and can both suppress the vital activity of pathogens and completely ignore the inflammatory processes).

Indications for appointment

The PC Mertz Instructions for Use recommends using it if:

pc merz from what

  • the patient had visualized symptoms of Parkinson’s disease (a tremor of the extremities is clearly visible, there is a suspicion of inadequate muscle tissue, etc.);
  • the patient was diagnosed with influenza A, or there was a need for prevention;
  • There is an acute problem of preventing the progress of neuralgia in shingles;
  • extrapyramidal disorders are required to level (for example, “nullify the negative” of neuroleptics).

Method of application and optimal dosage

For the tablet form of the drug, the following rules apply:

  • adults and children over 12 years old are prescribed one tablet (100 mg of reagent) per day for the first 4-7 days;
  • a further increase in the rate is made at the rate of “+1 pill / week” up to the achievement of the expected result (the number of receptions is increased up to two or three times);
  • The optimal daily dosage is from 2 to 6 units of the drug (depending on the stage of the disease).

On the other nuances of the mode of use of pills "PC-Mertz" instructions for use reports:

pc mertz drug description

  • The last daily dose of the medication should be used no later than 16.00 (judging by the comments, the ideal schedule has only two “control points”: 08.00 and 15.00);
  • the medicine should be taken with water;
  • Older patients, whose behavior has characteristic symptoms, recommended reduced dosage - 1 tablet in the morning during the entire health course (in the absence of visible positive changes, the rate is raised to 200 mg of amantadine sulfate per day, but this is done gradually and in the presence of a doctor) ;
  • in combination therapy, the schedule is chosen individually;
  • if the patient had previously undergone medical treatment by setting up a dropper with a solution of the specified substance, then the initial tablet dose is increased (at the discretion of the specialist).

In the case of a solution, the following official guidelines are relevant:

pc mertz composition

  • with the rapid aggravation of the situation (a sharp exacerbation of parkinsonism), intravenous infusion in the amount of 200 mg of amantadine sulfate may be required (1 bottle);
  • the maximum allowable rate of administration is 55 drops / minute (the total length of the procedure is about 3 hours; the number of repetitions is no more than three for every 24 hours);
  • changing the clinical picture for the better is a reason for refusing injections in favor of tablets (if we are talking about a stable patient, the oral form of treatment should last 2-4 weeks with a dose of at least 200 mg / day; when the patient’s condition is burdened by other infections or age, appoint 100 mg / day);
  • the presence of renal failure - a signal that the schedule of use of the drug should be adapted to the glomerular filtration rate.

Contraindications stated by the manufacturer

"PK-Mertz" (what exactly does this drug help with and what factors influence the choice of the optimal dosage,was mentioned above) is not recommended for use if:

pc merits instructions for use analogues

  • there is reason to believe that the patient suffers from individual intolerance to the ingredients;
  • severe cardiac arrhythmia or bradycardia was diagnosed;
  • the analysis showed an excessively low level of potassium / magnesium in the blood;
  • parallel treatment with budipin, its derivatives or other drugs, leading to prolongation of the Q-T interval;
  • recorded an imbalance in the kidneys.

All the above conditions are valid for the solution. In addition, infusions are contraindicated in children under 12 years of age, pregnant women and young mothers during lactation.

Likely side effects

We have already mentioned the “factor problem” of the use of the PC-Merz pharmacological product. Description of the drug will be incomplete without specifying atypical reactions of the body. Among them:

  • severe sleep disorders;
  • paranoid psychosis (high-risk group - people over 65);
  • orthostatic imbalances;
  • weakness;
  • headache;
  • temporary visual impairment;
  • overload of the cardiovascular system (from arrhythmias to "marble" skin);
  • local allergies;
  • nausea;
  • feeling of dry mouth.

PK Mertz: description of the mechanism of pharmacological interaction with other drugs

Drugs that stimulate the central nervous system and ethanol-containing reagents form extremely undesirable compounds upon contact with the components of PC-Merz. Instructions for use (analogs mainly interact according to the same principle, but other scenarios are likely during the complex therapy), in particular, it warns against parallel use of tricyclic and tetracyclic antidepressants, gyrase inhibitors and other antipsychotic drugs.

pc mertz instruction manual reviews

With the correct adjustment of the daily dose, joint reception with anticholinergic agents and anti-parkinsonic substances is quite acceptable.

Reviews, Comments, Medication Doubles

Despite the fact that "PK-Mertz" instructions for use (reviews left on the thematic forums, suggest that the drug helps even with severe pathologies) is primarily defined as a tool to combat rigidity, tremor and other symptoms of Parkinson's disease, many times positive dynamics were observed in the treatment of viral infections.This fact is explained by the fact that the mechanism of the hidden possibilities of the ingredients is not fully understood. For example, doublers such as Midantan, Viregit-K and Gludantan do not have this effect.

The professional controversy that has unfolded around the question of the expediency of the parallel appointment of Anapralin as a compensator for undesirable stress on the heart muscle deserves attention, but the final decision remains for the doctor who supervises the particular patient.

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