Bronchodilating drug "Ipratropium bromide": properties and indications
The medicine "Atrovent N", or "Ipratropiya Bromide", is a synthetic drug with a pronounced bronchodilating effect. It is a competitive antagonist, because it has a structural similarity with the acetylcholine molecule. The use of the drug "Ipratropia Bromid" allows you to effectively suppress reflex bronchoconstriction, block m-cholinergic receptors of the smooth muscles of the bronchi, reduce the secretion of bronchial glands and glands of the mucous membrane of the nasal cavity, prevent narrowing of the bronchi due to inhaling cold air or cigarette smoke. In addition, this tool significantly improves the conductivity of the AV type and increases the frequency of contractions of the heart.The greatest therapeutic effect in this case develops after only one - two hours after using the medicine. One of the main varieties of the drug "Ipratropia Bromide" today is the means "Fenoterol Ipratropium Bromide".
Forms of release
This medicine is produced mainly in the form of a solution for inhalation, contained in special dropper bottles, powder for inhalation, and also in the form of a metered aerosol for inhalation placed in aerosol cans with a mouthpiece and a valve. The composition of all these forms as a main component includes a substance such as ipratropium bromide. Thanks to this ingredient, the drug has a characteristic bronchodilator effect.
The medicine Ipratropia Bromide is recommended in the case of chronic obstructive pulmonary disease, sinus bradycardia, SA blockade, bradyarrhythmia, AV second-degree blockade or bradystolic form of atrial fibrillation. In addition, experts include in the list of direct indications for his appointment of bronchial asthma and bronchospasm, developed on the background of infection or as a result of surgical intervention.Also, the drug "Ipratropia Bromide" is recommended to be used during the preparation of the respiratory tract before the direct introduction of mucolytic drugs, antibiotics, cromoglicic acid or glucocorticosteroids. In addition, this medicine is indispensable when conducting a test for the reversibility of bronchial obstruction.
Assign the drug "Ipratropia Bromid" manufacturer strictly prohibits people with hypersensitivity to atropine and any of its derivatives, as well as in the event of an allergic reaction to excipients present in the composition of the product. Women who are waiting for a child should refrain from using this bronchodilator and, if necessary, replace it with any other medicine. With extreme caution, the drug "Ipratropia Bromide" is used in the obstruction of the urinary tract or angle-closure glaucoma. Patients younger than six years of age should be used only under the supervision of a physician.