The drug "Antisten". Instructions for use

For the treatment of cardiovascular pathologies today applies quite a lot of money.antisthen tabletsThe drug "Antisten" is considered one of the popular medicines recommended for patients with diseases of this kind.

Composition and dosage form

Means "Antisten" is available in the form of round biconvex tablets coated with a red shell, dosage of 20 mg. Contour cell packaging consists of PVC film and foil. The inner layer of tablets has a white or white-yellow shade. The product contains 20 mg of trimetazidine dihydrochloride, which is the active substance. In the medication there are also auxiliary components. These include: corn starch, magnesium stearate, povidone, mannitol, colloidal silicon dioxide, lactose, hydroxypropyl methyl cellulose, titanium dioxide, methyl cellulose, castor oil, Tween 80, acid red 2C, polyethylene glycol-4000.

Pharmacodynamics of the drug "Antisten"

Tablets have antihypoxic and antianginal effects. The drug improves the function, the metabolism of neurons and cardiomyocytes of the brain, prevents a decrease in the concentration of ATP, phosphocreatinin in cells. The medicine also supports contractility of the heart muscle. The tool prevents an increase in the level of calcium and sodium in cardiomyocytes, contributes to the normalization of the content of potassium ions in the cell, stabilizing the functions of membrane ion channels in conditions of acidosis. The drug "Antisten" prevents the destructive function of free radicals, prevents the active action of neutrophils in the ischemic area. The drug helps to preserve the integrity of the cell membrane, reduces the yield of cellular creatine phosphokinase. The medicine "Antisten" reduces the frequency of attacks in angina pectoris. After two weeks of use of the drug, a significant decrease in blood pressure drops and an increase in endurance to physical activity is observed. As a result of treatment with the medication in question, patients complain less of dizziness and tinnitus, their hearing and activity of the vestibular apparatus improves.In people with vascular eye disease, the functions of the eye retina are normalized.

antisthen instructions for use


After the penetration of the drug into the body absorption occurs quickly enough. The drug is almost completely absorbed from the digestive system. After 2 hours, the maximum concentration in the blood is reached, which is 55 ng / ml of trimetazidine. Means "Antisten" passes through histohematogenous barriers. After about five hours, half of the active substance is excreted in the urine.

Means "Antisten". Instructions for use. Indications

The drug is recommended to appoint people suffering from coronary artery disease. As part of a complex treatment, the remedy is used as a prophylaxis of strokes. The drug is prescribed for chorioretinal vascular disorders, dizziness caused by vascular disorders, cochleovestibular disorders of ischemic origin.

antistein instruction


The drug "Antisten" instructions for use does not recommend for intolerance to the drug, renal failure, impaired liver function of a pronounced nature. Contraindications include the prenatal period.During lactation, antisten is also not prescribed. Instructions for use does not recommend taking medication to persons under the age of 18. This is due to insufficient information about the safety of the drug.

Dosing regimen

The tool is taken orally during the meal. Daily dosage is 2-3 tab. This corresponds to 40-60 mg. The specified amount of the drug is recommended to be divided into 2-3 doses. The duration of a therapeutic or prophylactic course is set by a specialist personally for each patient. During therapy, one should not independently (without consulting with a doctor) change the regimen.


Side effects

The most frequently occurring undesirable effects of the Antisten product are instructions for use that include abdominal pain, diarrhea, indigestion, nausea and vomiting. The drug may provoke dizziness, migraine, itching, urticaria, asthenia. Some patients may have hot flashes of the face, orthostatic hypotension. Extrapyramidal disorders, in particular, tremor, rigidity, akinesia, are extremely rarely observed.Such symptoms, as a rule, are self-eliminated after discontinuation of the drug. To date, nothing is known about the drug overdose, since there have been no complaints. In this regard, a specific antidote does not exist. Presumably, overdose exacerbated adverse events. If you suspect poisoning means you must visit a doctor.

antisthen instructions for use

additional information

Currently, there is no information about the interaction of antisten with other drugs. The drug does not affect the ability to manage any motor transport and the performance of work in which a high speed of a psychomotor reaction is required. Analogues of the drug are the medicines "Carditrim", "Predizin", "Metagard", "Preductal".

Conditions of supply from the network of pharmacies and storage

The drug "Antisten" is recommended to be stored in a dry dark place out of the reach of children. The temperature should not exceed 25 degrees. Shelf life of the drug - 3 years. Do not take the drug after this time. The drug "Antisten" in pharmacies prescription.

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