Antianginal drug "Coraxan": instructions for use

Coraxan instructions for useThe drug "Coraxan" instructions for use is defined as an antianginal agent, actively used for the treatment of various diseases of the cardiovascular system. The basis of this medication is specific and selective inhibition of the If-channels of the sinus node, which control diastolic depolarization and regulate the frequency of contractions of the heart. At the same time, the main pharmacological advantage of the antianginal drug "Coraxan" (confirms the instructions for use) compared with its analogues is dose-dependent ability to reduce heart rate. If we talk about the features of the perception of this drug by the human body, then its maximum plasma concentrations begin to be noted 1.2-1.6 hours after administration, and the so-called half-life averages 11 hours.

Description of the dosage form

coraxan 5Antianginal agent Coraxan is produced (instructions for use are always included) in the form of orange tablets in the dosage of 7.5 and 5 mg. Ivabradine hydrochloride is included in the composition of this drug as an active ingredient. Silicon dioxide, lactose monohydrate, starch, maltodextrin and magnesium stearate act as auxiliary components. The tablet shell contains hypromellose, macrogol 6000, dye and glycerol. In addition, magnesium stearate and titanium dioxide are present in a small volume.

Area of ​​use

Take pills "Coraxan" (5 or 7.5 mg) manufacturer recommends for the treatment of stable angina. In addition, this antianginal drug should be used to reduce the risk of complications in people with chronic heart failure.

List of contraindications

coraxan reviewsPrescribing medicine "Coraxan" strictly forbids the application if the patient suffers from bradycardia, acute myocardial infarction, sinoatrial blockade or AV-blockade of the third degree. In cardiogenic shock,Severe arterial hypotension, unstable angina pectoris, or established liver failure should also be discontinued from taking these pills. In addition, contraindications include such conditions as, for example, lactase deficiency, weakness of the sinus node, lactose intolerance, an allergic reaction to ivabradine or any other substance that is present in the composition of the drug Coraxan. Reviews of people who have previously taken this tool, also note the undesirability of its use simultaneously with antibiotics, macrolides, antifungal drugs from the pharmacological group of azoles and other strong inhibitors of the isoenzyme of the so-called cytochrome P450 3A4 system. Pregnant women, women who are breastfeeding, and patients who are under the age of eighteen, should not use the coangarian antianginal remedy. With great caution, it is necessary to prescribe this drug in patients with moderate liver failure, arterial hypotension, renal failure and AV second-degree blockade.

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